2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B1562
    Bopindolol 62658-63-3 98%
    Bopindolol ((±)-Bopindolol) is an orally active antagonist of β-adrenoceptors (ARs) with partial agonist activity. Bopindolol is non-selective for β1- and β2-ARs and has low affinity for β3-AR subtype. Bopindolol has intrinsic sympathomimetic as well as membrane stabilizing actions, inhibits renin secretion, and interacts with 5-HT receptors. Bopindolol is a proagent of Pindolol (HY-B0982). Bopindolol can be used for essential and renovascular hypertension research.
    Bopindolol
  • HY-B1656
    Fomocaine 17692-39-6 98%
    Fomocaine (P 652) is an orally active local agent that can suppress or relieve pain. Fomocaine shows antiarrhythmic activity.
    Fomocaine
  • HY-B1660
    Guanadrel sulfate 22195-34-2 98%
    Guanadrel sulfate is an orally active, potent and postganglionic sympathetic inhibitor. Guanadrel sulfate lowers blood pressure by reducing systemic vascular resistance with little effect on cardiac output. Guanadrel sulfate is promising for research of hypertension.
    Guanadrel sulfate
  • HY-B1661
    Hexamethonium chloride 60-25-3 98%
    Hexamethonium Chloride Dihydrate is a synthetic organic compound commonly used as a ganglion blocking agent, which means it blocks the transmission of nerve impulses between ganglion cells in the autonomic nervous system. Hexamethonium Chloride Dihydrate is used in various medical applications such as lowering blood pressure or inhibiting certain types of neuropathic pain. It works by inhibiting the release of acetylcholine, a neurotransmitter that plays a key role in regulating many bodily functions.
    Hexamethonium chloride
  • HY-B1708
    Nordefrin 74812-63-8 98%
    Nordefrin ((±)-Cobefri), a Norepinephrine (HY-13715) derivative, is a vasoconstrictor agent.
    Nordefrin
  • HY-B2081
    Etozolin 73-09-6 98%
    Etozolin (W-2900A) is a diuretic agent. Etozolin inhibits fluid and electrolyte reabsorption in the loop of Henle. Etozolin can be used in research of congestive heart failure, hypertension and edema.
    Etozolin
  • HY-B2096
    Oleic acid ethanolamine 2272-11-9 98%
    Oleic (9-cis-Octadecenoic) acid ethanolamine consists of oleic acid and ethanolamine. Oleic acid ethanolamine has sclerotherapeutic activity. Oleic acid ethanolamine can cause inflammatory reaction in the intimal endothelium of the vein.
    Oleic acid ethanolamine
  • HY-D1073
    DiOC7(3) 53213-83-5 98%
    DiOC7(3) (3,3'-Diheptyloxacarbocyanine iodide) is a green membrane potential probe (Ex=450-490 nm, Em=510-520 nm). DiOC7(3) can be used to quantify the vascular densities.
    DiOC7(3)
  • HY-D1408
    DMTr-4'-Me-U-CED-TBDMS phosphoramidite 1260508-74-4 98%
    DMTr-4'-Me-U-CED-TBDMS phosphoramidite (DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-Me-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure.
    DMTr-4'-Me-U-CED-TBDMS phosphoramidite
  • HY-D1409
    DMTr-4'-F-U-CED-TBDMS phosphoramidite 98%
    DMTr-4'-F-U-CED-TBDMS phosphoramidite (DMTr-4'-F-uridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-F-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure.
    DMTr-4'-F-U-CED-TBDMS phosphoramidite
  • HY-D1463
    Nile Blue Methacrylamide 699018-10-5 98%
    Nile Blue Methacrylamide is a Nile Blue-based nanosized pH densor that can be used for simultaneous far-red and near-infrared live bioimaging.
    Nile Blue Methacrylamide
  • HY-N0302
    Gypsoside 15588-68-8 98%
    Gypenoside is a triterpene saponin from gypsophila paniculata L.
    Gypsoside
  • HY-N1006
    10-Hydroxyscandine 119188-47-5 98%
    10-Hydroxyscandine is an alkaloid from Melodinus tenuicaudatus. 10-Hydroxyscandine can be used for the research of hernia, dyspepsia, abdominal pain, and rheumatic heart.
    10-Hydroxyscandine
  • HY-N1088
    Vindorosine 5231-60-7 98%
    Vindorosine is an alkaloid from Catharanthus trichophyllus Roots. Vindorosine relaxes renal arteries.
    Vindorosine
  • HY-N1102
    Vasicinol 5081-51-6 98%
    Vasicinol is a reversible inhibitor of sucrase (IC50: 250 μM). Vasicinol is a HbF inducer. Vasicinol also inhibits Angiotensin-converting Enzyme (ACE). Vasicinol is apyrroquinazoline alkaloid that can be isolated from Adhatoda vasica.
    Vasicinol
  • HY-N1208
    Spiradine F 21040-64-2 98%
    Spiradine F is a main alkaloidal component of spiraea japonioa L. fil. Spiradine F derivative can inhibit platelet-activating factor (PAF)-induced platelet aggregation.
    Spiradine F
  • HY-N1344
    Robtin 4382-34-7 98%
    Robtin (Compound 4) is a natural product isolated and purified from Sophora yunnanensis. Robtin has cardiotonic activity.
    Robtin
  • HY-N1553
    Pseudolaric acid D 115028-67-6 98%
    Pseudolaric acid D is a compound with oral activity that can be isolated from Pseudolarix kaempferi Gorden. Pseudolaric acid D can significantly improve lipid metabolism, reduce atherosclerotic lesion area, and alleviate atherosclerotic changes in vascular wall. Pseudolaric acid D significantly inhibits the inflammatory reaction.
    Pseudolaric acid D
  • HY-N1620
    1-Cinnamoylpyrrolidine 52438-21-8 98%
    1-Cinnamoylpyrrolidine (Compound 3), a crude extract prepared from Piper caninum, is a DNA strand scission agent, induces the relaxation of supercoiled pBR322 plasmid DNA. 1-Cinnamoylpyrrolidine (Compound 4) inhibits platelet aggregation induced by PAF with an IC50 of 37.3 μM.
    1-Cinnamoylpyrrolidine
  • HY-N1723
    2-Deacetoxytaxinine B 191547-12-3 98%
    2-Deacetoxytaxinine B is a potent antiplatelet agent.
    2-Deacetoxytaxinine B
Cat. No. Product Name / Synonyms Application Reactivity